Melphalan-d8 Dihydrochloride - Names and Identifiers
Melphalan-d8 Dihydrochloride - Physico-chemical Properties
Molecular Formula | C13H18Cl2N2O2
|
Molar Mass | 305.20022 |
Melting Point | 164-1700C (dec) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Storage Condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
Stability | Hygroscopic |
Melphalan-d8 Dihydrochloride - Introduction
Melphalan-d8 Dihydrochloride (Melphalan-d8 Dihydrochloride) is an organic compound with the chemical formula C13H14D8Cl2N2O2. It is a stable deuterium isotope labeled Melphalan, commonly used in drug metabolism and pharmacokinetic studies.
Melphalan is a nitrogen mustard compound commonly used in anti-cancer therapy. Melphalan-d8 Dihydrochloride is the substitution of deuterium into the Melphalan molecule, increasing the sensitivity of its analytical use while maintaining the chemical and biological activity of the original compound.
Melphalan-d8 Dihydrochloride is commonly used in pharmacokinetic studies for the Study of Drug absorption, distribution, metabolism, and excretion (ADME), as well as for the study of drug-drug interactions. It can also be used as a quality control standard and an internal standard for mass spectrometry analysis.
The method of preparing Melphalan-d8 Dihydrochloride is usually obtained by reacting raw materials that have been labeled with deuterium. The specific preparation method may be a synthetic method provided by a commercial institution, or the synthesis may be carried out according to the relevant literature.
Regarding safety information, Melphalan-d8 Dihydrochloride is a chemical with certain toxicity. When using, should follow the safety procedures, avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with plenty of water and seek medical treatment. Please read and understand the relevant safety data sheet (SDS) and operating instructions before use, and take appropriate protective measures.
Last Update:2024-04-09 20:02:46